During a colonoscopy, which instrument is used to obtain tissue samples?

• A. Endoscope
• B. Sterile biopsy forceps
• C. Otoscope
• D. Syringe

Answer: (B)

When a colonoscopy requires tissue sampling, sterile biopsy forceps are used. These forceps pass through the endoscope’s working channel, clamp a small piece of the colon lining, and retrieve it for pathology. The endoscope itself is the visualization tool, not the sampling instrument. The other options don’t apply here: an otoscope is for the ear, and a syringe is for injections or fluid collection, not for taking tissue samples during colonoscopy.