Which medication is a steroid-free anti-inflammatory cream that can be used as an alternative to steroids for eczema?

• A. Hydrocortisone cream
• B. Pimecrolimus cream
• C. Antifungal cream
• D. Antibiotic ointment

Answer: (B)

The key idea is identifying a non-steroidal option that reduces eczema-related inflammation. Pimecrolimus cream is a topical calcineurin inhibitor that acts as an immunomodulator. It blocks T-cell activation and lowers inflammatory cytokine production, helping to calm the skin without using corticosteroids. This makes it a suitable steroid-free alternative for eczema, especially on delicate areas like the face or skin folds and for long-term management when avoiding steroid exposure is preferred. It may cause a brief burning sensation at first use and isn’t a treatment for infections, unlike antifungal or antibiotic creams. Hydrocortisone is a steroid, which isn’t steroid-free; antifungal and antibiotic creams target infections rather than the inflammatory immune response in eczema.