Which statement about injections is true for adults?

• A. Injections of 2 to 5 mL; any dose 4 mL or above should be divided and administered as two injections.
• B. Injections of 1 to 2 mL only.
• C. A single dose should not be divided under any circumstance.
• D. All injections must be given intramuscularly regardless of volume.

Answer: (A)

Focus on how much fluid you can safely give in a single injection for adults and what to do when the dose is large. In adults, the amount injected at one site depends on the route and muscle, but many intramuscular injections can be given in up to roughly 2 to 5 mL at a single site. When the dose reaches 4 mL or more, splitting it into two injections at separate sites is a common practice to reduce tissue irritation and ensure proper absorption. This makes the statement true because it reflects a practical rule: keep each injection within a tolerable volume and divide larger doses into two injections. Other routes exist with different limits, and not every injection must be intramuscular, so those alternatives don’t fit as a universal rule.